The truth is, a nice gift shouldn't be specific to any holiday season. You love your Christian friend, you love your Jewish friend, you love your Atheist friend, you love your Trekker friend, you love your friend. Buy 'em a nice bottle of wine to show you care. If they like to drink, they'll appreciate it.
Hey, if it's not your thing, we respect that. Cultural, religious, personal, do what's right for you. But if it is your thing, now's a good time to stock up! That way, you'll be ready to share a glass with somebody, be it Santa or your brother or that lonely neighbor across the hall. Maybe make a new friend this holiday?